Haven't been posting for awhile as I've been working on getting better while being treated for my myopathy.
But I check back once in awhile and saw this thread so I'll toss in some of my experience.
I have whats known as necrotizing autoimmune myopathy, can be caused by statins, fibrates and unknown.
I don't think my disease ever progressed to causing rhabdomyolysis (which it can) but if someone has had rhabdomyolysis along with muscle pain and fatigue they should have it checked out.
Anybody that has had rhabdomyolysis should have a blood CPK ( creatine kinase) to determine muscle damage.
Other tests for inflammation and muscle damage can determine if its inflammatory (autoimmune) or not.
The joker in the deck is the newish necrotizing autoimmune myopathies are autoimmune but without the usual inflammation present.
Its considered one of the "toxic" myopathies, usually caused by drugs or chemicals.
Its becoming evident that a larger amount of people have adverse effects to lipid lowering drugs that do not end after stopping the drugs.
It took a couple of electromyogram tests, a muscle biopsy and change in neurologists before I was started on autoimmune treatments.
I've also tested way over normal for aldolase which shows muscle damage.
After 10 months of IVIG treatment which ended in September I had improved symptoms but CPK did not drop.
I started on low dose methotrexate in late July and have slowly been improving since.
Aldolase dropped almost to normal and CPK dropped about a hundred points three months after starting.
I also take the B vitamins, mfolate, coq10 and branch chain amino acids that help.
The University of Washington at St Louis Neuromuscular page is a good source of further information, they've just recently updated the myopathy pages.
They are one of the top research universities in the US
The fibrate caused myopathy section (I was on fibrates for 8ish years) show reduced fatty acid and branch chain amino acids oxidation and reduced CPT activity resulting from that disease.
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Home
http://neuromuscular.wustl.edu/
Rhab section
http://neuromuscular.wustl.edu/msys/myoglob.html