Hi all,
I decided to do the 23andme test to see if it would tell me why I cannot tolerate methylfolate. I take methyl b12 in high doses without issue and that has cleared my hyperhomocystinemia. I have depression and lethargy and was hoping to take higher dose of 5mthf. When I first took 5mthf I felt really good but then dissolved into rage and tears. I am having trouble trying to figure out what is going on. I had a hair test (I know not reliable) a while back that showed really high phenylalanine and really low taurine. If anyone has any guidance to offer I would really appreciate it.
COMT V158M rs4680 AA +/+
COMT H62H rs4633 TT +/+
COMT P199P rs769224 AG +/-
VDR Bsm rs1544410 TT +/+
VDR Taq rs731236 GG -/-
MAO-A R297R rs6323 GT +/-
ACAT1-02 rs3741049 AG +/-
MTHFR C677T rs1801133 AG +/-
MTHFR 03 P39P rs2066470 GG -/-
MTHFR A1298C rs1801131 GT +/-
MTR A2756G rs1805087 AA -/-
MTRR A66G rs1801394 AG +/-
MTRR H595Y rs10380 CT +/-
MTRR K350A rs162036 AG +/-
MTRR R415T rs2287780 CC -/-
MTRR A664A rs1802059 AG +/-
BHMT-02 rs567754 CC -/-
BHMT-04 rs617219 AA -/-
BHMT-08 rs651852 CC -/-
AHCY-01 rs819147 CT +/-
AHCY-02 rs819134 AG +/-
AHCY-19 rs819171 CT +/-
CBS C699T rs234706 AG +/-
CBS A360A rs1801181 AG +/-
CBS N212N rs2298758 GG -/-
SHMT1 C1420T rs1979277 AG +/-
I decided to do the 23andme test to see if it would tell me why I cannot tolerate methylfolate. I take methyl b12 in high doses without issue and that has cleared my hyperhomocystinemia. I have depression and lethargy and was hoping to take higher dose of 5mthf. When I first took 5mthf I felt really good but then dissolved into rage and tears. I am having trouble trying to figure out what is going on. I had a hair test (I know not reliable) a while back that showed really high phenylalanine and really low taurine. If anyone has any guidance to offer I would really appreciate it.
COMT V158M rs4680 AA +/+
COMT H62H rs4633 TT +/+
COMT P199P rs769224 AG +/-
VDR Bsm rs1544410 TT +/+
VDR Taq rs731236 GG -/-
MAO-A R297R rs6323 GT +/-
ACAT1-02 rs3741049 AG +/-
MTHFR C677T rs1801133 AG +/-
MTHFR 03 P39P rs2066470 GG -/-
MTHFR A1298C rs1801131 GT +/-
MTR A2756G rs1805087 AA -/-
MTRR A66G rs1801394 AG +/-
MTRR H595Y rs10380 CT +/-
MTRR K350A rs162036 AG +/-
MTRR R415T rs2287780 CC -/-
MTRR A664A rs1802059 AG +/-
BHMT-02 rs567754 CC -/-
BHMT-04 rs617219 AA -/-
BHMT-08 rs651852 CC -/-
AHCY-01 rs819147 CT +/-
AHCY-02 rs819134 AG +/-
AHCY-19 rs819171 CT +/-
CBS C699T rs234706 AG +/-
CBS A360A rs1801181 AG +/-
CBS N212N rs2298758 GG -/-
SHMT1 C1420T rs1979277 AG +/-