Hey everyone.
Going through heartfixer and have the following issues:
As you can see, I'm +/- for both COMT and VDR.
From my research, COMT +/+ means I degrade dopamine slowly, so I have more methyl groups floating around. But the VDR issue with +/+ means I need more methyl donoars to function properly.
So since I'm +/-, I'm assuming I'm somewhere in the middle, but does this just cancel each other out? So the COMT has more methyl donors floating around, but then the VDR takes those methyl donors up?
Here's the rest of my chart if it makes any difference:
thanks for any insights into this. heartfixer said regarding this combo: Multiple (+/-) combinations of COMT and VDR Taq are possible. We will address these “intermediate” genotypes with intermediate levels of methyl group supplementation. I will be more specific on your individual report.
Going through heartfixer and have the following issues:
COMT V158M
rs4680
AG
+/-
COMT H62H
rs4633
CT
+/-
COMT P199P
rs769224
GG
-/-
VDR Bsm
rs1544410
CT
+/-
VDR Taq
rs731236
AG
+/-
As you can see, I'm +/- for both COMT and VDR.
From my research, COMT +/+ means I degrade dopamine slowly, so I have more methyl groups floating around. But the VDR issue with +/+ means I need more methyl donoars to function properly.
So since I'm +/-, I'm assuming I'm somewhere in the middle, but does this just cancel each other out? So the COMT has more methyl donors floating around, but then the VDR takes those methyl donors up?
Here's the rest of my chart if it makes any difference:
VDR Fok-I
not found
n/a
n/a
MAO A R297R
rs6323
T
+
ACAT1-02
rs3741049
GG
-/-
MTHFR C677T
rs1801133
GG
-/-
MTHFR 03 P39P
rs2066470
GG
-/-
MTHFR A1298C
rs1801131
GT
+/-
MTR A2756G
rs1805087
AG
+/-
MTRR A66G
rs1801394
AG
+/-
MTRR H595Y
rs10380
CC
-/-
MTRR K350A
rs162036
AG
+/-
MTRR R415T
rs2287780
CC
-/-
MTRR S257T
not found
n/a
n/a
MTRR A664A
rs1802059
AG
+/-
BHMT-01
not found
n/a
n/a
BHMT-02
rs567754
CT
+/-
BHMT-04
rs617219
AC
+/-
BHMT-08
rs651852
CT
+/-
AHCY-01
rs819147
TT
-/-
AHCY-02
rs819134
AA
-/-
AHCY-19
rs819171
TT
-/-
CBS C699T
rs234706
GG
-/-
CBS A360A
rs1801181
AA
+/+
CBS N212N
rs2298758
GG
-/-
SUOX S370S
not found
n/a
n/a
NOS3 D298E
not found
n/a
n/a
SHMT1 C1420T
rs1979277
AG
+/-
thanks for any insights into this. heartfixer said regarding this combo: Multiple (+/-) combinations of COMT and VDR Taq are possible. We will address these “intermediate” genotypes with intermediate levels of methyl group supplementation. I will be more specific on your individual report.
