filfla4
Senior Member
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y\Great! Thanks for posting.
The start of the article (which allows comments) is available online but the full thing (presumably including the ability to comment) is behind a paywall:
http://www.thetimes.co.uk/tto/science/article3746102.ece
Any subcribers who can comment and mention the UK biomedical charities, or Maria's Rituximab fundraising drive? I think these kind of articles attract PWME who aren't even aware that these charities exist. I think they're a good recruiting ground.
Good news but I'll have too wait a while before I do my happy dance followed by my I told you so dance. Somewhere as we type Weasel - Whitewash and Co are busy planing a counter (debunking) offensive.
This is semi-old news, I think, but what is new is that the media is picking up on it. That is a good sign. It might also be that I am misremembering as similar research was done on OI if I recall correctly, and the CFS study is really new. Either way, I like this trend of isolating tissue and then subjecting it to tests under stress in controlled conditions. Its paid off for OI, and FM, and now maybe CFS. Hard to study stuff is easier to study if its isolated, though you then lose the complexity of interaction that may make things happen differently in the body.
Now if they did cytokine testing and energy production testing under these conditions, would we get diagnostic biomarkers?
In the study, scientists took muscle biopsies from ten patients and ten healthy but sedentary volunteers.
The muscle cells were grown into small pieces of muscle and then subjected to “exercise” in the form of electrical impulses.
The cells from ME patients produced on average 20 times as much acid when exercised, suggesting an underlying cause for the aching muscles that patients often experience as soon a they begin to exercise.
The cells also showed other abnormalities, such as reproducing more slowly.