Heaps, I have tried pretty much all of the things you have mentioned above without any success. I have had this for around 11 years now. I was diagnosed +ve for lyme around 6 years ago by an LLMD at the Breakspear hospital in UK (testing done at Igenex in USA and Brehmen Germany) and was on different courses of anti-biotics for well over 2 years - doxycycline,claryromycin,amoxycillin, anti-fungals, riamphin, ceforoxime, anti malarial tablets and others I cant remember - no luck. I also had over 6 months of treatment for adrenal malfunction , based on 24 hr saliver and urine testing at the climer institute in USA - no luck. I have had ATP profile testing done and was shown to have very poor ATP function (Sarah M's clinic in UK) - did a 6 month stint of a variety of supplements and self injected vitamin b and magnesium twice a day for that period - no luck. i did over 6 months of equilibrant at 6 tablets a day - no improvement. I did the lightning process and also had 6 sessions of relaxation hypnotherapy - no good. I have also done CBT and GET and ended up falling out with the instructors, I have seen a psychiatrist who said I was in perfect mental health. I have tried a multitude of probiotics , and diets, I have tried LDN for 6 months - no effect. I have tried worming tablets and other strange things.One thing that has pretty much sorted out my IBS has been the kefir and colostrum mixture I have been drinking twice a day for about 9 months now - so I would definitely recommend this. I was one of the very first 12 people in the UK to get tested for XMRV. These are obviously not in the order listed (and there are probably others I cant remember). Originally I was treated on private health care until they stopped paying as they said it was a chronic long term condition. I have paid probably around 10k out of my own pocket (+10K on private health care) as well and since losing my job (a well paid senior IT manager) have had to choose my pathways with a lot more monetary caution. Sorry for the rant but I expect many others on here are feeling the same as me and it is good to get it off my chest.