Anyone reading this thread & considering they may have fragile connective tissue due to a genetic reason, should not only consider Ehler's Danlos Syndrome as a possibility. Marfan Syndrome & Loeys-Dietz Syndrome are also possibilities.
People with Loeys-Dietz Syndrome are not necessarily hypermobile.
One feature of Loeys-Dietz Syndrome I find interesting is:
"Allergies to both food and things in the environment"
From this fact sheet explaining the difference between Loeys-Dietz Syndrome and Marfan Syndrome. Why a correct diagnosis is important.
http://www.marfan.org/cms/uploaded_files/8XJIUG81F3/89/docs/factsheet_ldsormfs.pdf
"WHY IS IT IMPORTANT TO HAVE A CORRECT DIAGNOSIS?
Medical care for LDS is not the same as for MFS. The most important difference is the care of the aorta and
other blood vessels. The care is different because life-threatening aneurysms in LDS are more likely to tear
and rupture at smaller sizes than in people who have MFS. In LDS, tears and ruptures can also happen at
younger ages and in locations not usually seen in MFS. For these reasons, surgery to repair aneurysms is
often done earlier in LDS. In addition, imaging tests must look at blood vessels throughout the body using
either CT or MR scans from the top of the head to the top of the legs.
There are other LDS medical problems not seen in MFS that need special care. These include cervical spine
instability (slipping of the upper part of the spine), congenital heart problems (heart defects at birth), allergies,
chronic gastrointestinal problems, rupture of the spleen and bowel, and rupture of the uterus during pregnancy.
LDS medical problems can be managed, but a person needs a correct diagnosis to find the right LDS medical
care and counseling."