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posting this as i think it will be of interest to most of us.
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If cortisol is shown to be low on testing, I think it is a mistake to only supplement with DHEA and hope that will bring up the cortisol level somehow because it generally won't be able to do so by itself. Most of the time one will need both HC and DHEA to correct a deficiency.i think its important to have good dhea levels before one looks at increasing a low cortisol level. Also early stages of adrenal fatigue cortisol is high and dhea drops off, this would also be an important time to look at dhea supplements as they help counteract the negative aspects of cortisol. cortisol/dhea are a yin and yang type of relationship.
If cortisol is shown to be low on testing, I think it is a mistake to only supplement with DHEA and hope that will bring up the cortisol level somehow because it generally won't be able to do so by itself. Most of the time one will need both HC and DHEA to correct a deficiency.
I do agree that there is a stage where cortisol and dhea have a yin and yang relationship but that is not always the case. In later stages of HPA dysfunction, cortisol and DHEA can both be low and there is no evidence that shows that increasing DHEA further lowers cortisol. Instead, the studies that have been done show that those with Addison's disease (ie no cortisol production) do much better when DHEA is added into the mix.
DHEA seems to be a hormone where the form and brand are crucially important. The lipid matrix or micronized forms seem to be vastly superior to other forms in terms of absorption and effect.
Ema, you state "DHEA seems to be a hormone where the form and brand are crucially important. The lipid matrix or micronized forms seem to be vastly superior to other forms in terms of absorption and effect."
How would I know if the DHEA that I'm taking is the correct one? I just grabbed whatever I found at the pharmacy. Is there a particular brand I should be using? Or something I should be looking for on the bottle? (I'm taking 25 mg in the morning so I can sleep at night.)