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Created in 2008, Phoenix Rising is the largest and oldest forum dedicated to furthering the understanding of, and finding treatments for, complex chronic illnesses such as chronic fatigue syndrome (ME/CFS), fibromyalgia, long COVID, postural orthostatic tachycardia syndrome (POTS), mast cell activation syndrome (MCAS), and allied diseases.
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Rich, is it unusual to get a response to just a 1/4 tablet of the NHF? Because I could hardly sleep at all Tuesday night.
And how about this. I added 2 drops hydroxy B12 on Thursday, and 2 drops of methyl B12 on Friday along with 1/2 tab of MegaFolinic. On Thursday, I organized my kitchen cabinet and herbs. On Friday, I went shopping and organized my clothes closet and tried on different outfits for hours. This after being nearly housebound and sometimes unable to get out of bed! And I particularly suffered from lack of executive function - planning, organizing and execution of tasks.
Although I only got 3 1/2 hours of sleep for three out of four of those nights, I didn't make the connection to the SMP - I never dreamed I'd respond to such a low dose. It was supposed to be a trial! I thought I was just testing them for tolerance.
By Saturday, I started thinking that I had in fact kick started the methylation cycle, and googled up Dr. Solomon's article. I realized she had a slightly different take on things, but the point was that my adrenals might be working better because methylation is important to their function. That's when I figured out that the extra energy and insomnia might be from too much cortisol: last week I accidentally took a double dose of HC in the afternoon and it had a similar effect on me.
Yesterday, I just took 5 mg. of HC in the morning. I went all day without napping although I did try to go to sleep a few times. By night, enough cortisol apparently washed out of my system, because I was able to sleep 8 hours, with three brief awakenings and only a little melatonin. Today I'll do the same thing, unless I get droopy and need to take more, and see if I sleep better. Then on Monday I'll visit my acupuncturist/MD. It will be interesting to see what my pulses show!
Hi Rich,
Thank you for the information. Can you recommend a qualify brand of methylfolate/folate (if methylfolate and folate are the same material). From your explanation, correct me if I'm wrong, I guess Fred's protocol is safer but maybe there are other aspects so anyway I ask- What is considered the most secure protocol for methylation? Do you know if improving methylation process is considered better than heavy metals detox in terms of safety and duration's process?
I still haven't seen the attached video but I'd like to know if it's also possible to do both processes, methylation and heavy metals detox, at the same time?
In which brand it's technically possible to open the capsule and use just a part of the amount?
Do you also treat in people using this method or can recommend on a doctor or a therapist?
Rachel.
Hi, Mimi.
Yes, some people have big responses to small dosages of the supplements in the simplified methylation protocol. Some people report that they have to start with "crumbs" of the supplements.
This protocol is designed to address the root issue in the pathophysiology of ME/CFS. As such, it can correct various aspects that have been treated downstream using drugs or hormone supplements. I wouldn't be surprised if that happened with you HPA axis. Some people have reported similar things involving their thyroid hormone supplementation. They have had to decrease or discontinue it because they developed HYPERthyroid symptoms after starting the methylation protocol.
You may have to adjust the dosages of the supplements to give the best results for your particular case.
I recommend working with your physician with regard to decreasing the dosages of prescribed hormone supplementation.
Best regards,
Rich
Thanks, in my country I didn't find that kinds of supplements. Do you know if Solgar folate 800 mcg can be divided and if it's also recommended?
Hi Rich,
Thanks for your reply. It's been a week now, and I am amazed that I can just walk around. I mean, I was nearly bedridden a week ago at this time. And now I can do things. Like yesterday, I took my mom out to lunch for her birthday, driving from the South Bay to Portola Valley and from there to Half Moon Bay and back. And the night before, I made it to a family dinner in Menlo Park. I also watched an aikido class and played around a little after class. I think I might even be able to practice again someday. I don't know how soon, but I'm thinking weeks, rather than months. I need basic conditioning. And a job. And a life. And the ability to do normal things, which is coming back, thanks to you and Dr. Yasko.
I've been sick for 18 1/2 years, very ill for the last 5 and desperately ill for the last 4 months. So you can imagine how I"m trying to wrap my head around suddenly being well. How well can I be? Will I be? Will it stay? I feel like my health is a mysterious chimera that comes and goes with a will of its own. I pray that it has come to stay. And if it's just a matter of a little nutrition, why not? I am quite amazed and profoundly grateful. Thank you so much for this Simplified Protocol.
Mimi
P.S. Regarding working with a physician and dosing advice. I do muscle testing on myself, as well as pulse reading, but to be sure, I visited my doctor yesterday. He confirmed that my pulses were stronger and we discussed my dosage. I sleep 7-8 hours on 5 mg. but only 3-4 hours when I increase my dose. So 5 mg. looks good for now, but we'll keep a close watch.
Regarding stearic acid, one of the FolaPro capsulae's ingredients -are there also negative opinions about this ingredient as about the vegetable stearate?
Is it necessary to do genetic tests before taking the supplements Alice mentioned above?