This is what my doctor recommended today. I wanted to check with the experts (you guys) first to see what you think. Has anyone had these and did they help? Were there any bad reactions to them?
Hi Alwayshopeful,
I did a small (n=10) trial of people, including myself, with glutathione. Each and every person had been successful at healing with mb12/adb12/Metafolin. Each found they rapidly developed glutathione "detox" which turned out to be an extreme methylfolate deficiency followed up with mb12 and then adb12 deficency symptoms. It stopped methylation and healing within 2 hours. It flushed massive amounts of b12 out of the body in urine. It casue an large increase in inflammation and most all of the methylfolate deficiency symptoms starting in hours. Several had lasting neurological damage.
I have still not recovered some neurological function I lost during the glutathione trial and the neurologicval damage it did. In addition, several people who were taking glutathione when they satarted the active b12 protocol, while the had some relief from some neurological pain as it further numbed and damged the nerves, they had no healing response at all until the gutathione or precursors were stopped, then healing started,
It appears that those who have a beneficial effect are already so deficient of mb12,adb12 and methylfolate with methylation shut down that they are already as severely deficienct as they can be and so have no change in that. Thise who have hyper-response to these vitamins find that glutathione provides "relief" by flushing the b12 from the body and bloacking the methylfolate from use and damaging the nerves further. As the risk of permanent brain damage appears high with this I would not suggest taking it. The risk from glutathione is probably 10,000 times greater than from anything else a person might take and does not appear to be tied to any genetics. IT combines with all forms of b12 and flushes them from the body and the methylfolate becomes useless in any quantity because off the "methy-trap" with the methylfolate flushed from the cells.
I think it is quite dangerous fad. One MD researcher I spoke with studing inflammation and b12 said "There is no safe way to take glutathione."
Taking glutathione could be one of thse mistakes that a person might regret for the rest of their life.
DISCLAIMER
I am a self taught systems analyst and consultant. I am not credentialed, certified or licensed to do anything besides drive a car. I have been disabled by the disease processes being discussed and affecting neurology in a multitude of ways for 10 years and impaired in a variety of ways and levels for 54 years before that. Everything I say is my opinion, synthesis, understanding or otherwise of my own creation except direct attributed quotes. Approximate paraphrases are also my interpretation of what I have read. All of this is at best my data analysis, understanding, synthesis and hypotheses and not to be construed as medical advice. I am not responsible for anything you do with any information provided in any way. Anything you do is your own responsibility and at your own risk. There are no published peer reviewed studies backing up my opinions or statements, except the incidental ones quoted or implicit in my synthesis or understanding, and then only in so far any reading of such papers may confer. Your interpretations, actions and variations of what I say are strictly at your own risk.