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Hydroxocobalamin could be directly helpful in some types of POTS, by regulating NO.
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Created in 2008, Phoenix Rising is the largest and oldest forum dedicated to furthering the understanding of, and finding treatments for, complex chronic illnesses such as chronic fatigue syndrome (ME/CFS), fibromyalgia, long COVID, postural orthostatic tachycardia syndrome (POTS), mast cell activation syndrome (MCAS), and allied diseases.
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Hi, all.
For what it's worth, I think that treating the partial methylation cycle block in ME/CFS so that glutathione can come back up to normal is likely to restore both aldosterone and antidiuretic hormone secretion, and thus bring the total blood volume back up to normal, correcting the POTS and OH in many cases.
Best regards,
Rich
Hydroxocobalamin could be directly helpful in some types of POTS, by regulating NO.
Hi, ramakentesh.
No. That's why I wrote "I think..."
As I recall, I have heard from a couple of people who found that doing the methylation treatment did help with orthostatic problems, but it hasn't been looked at with a clinical study.
I'm basing the "I think" on my hypothesis, which is consistent with known biochemistry and physiology, as far as I can tell, but it is still just a hypothesis.
Best regards,
Rich
I don't have POTS; my OI is neurally mediated hypotension. I was on Florinef for a little over 2 years, and it didn't seem to do anything one way or the other. The only side effect I experienced was that I was hungry all the time.
anybody know if florinef causes weight gain beyond just water weight ?