I just happened to come across the following:
It's free at: http://www.trialsjournal.com/content/12/S1/A144
It's late here so on a first read I'm having difficulty understanding it. Perhaps together we can break it down.
How do treatments for chronic fatigue syndrome work? Exploration of instrumental variable methods for mediation analysis in PACE a randomised controlled trial of adaptive pacing therapy, cognitive behaviour therapy, graded exercise therapy, and specialist medical care
Kimberly Goldsmith1*, Trudie Chalder1, Paul White2, Michael Sharpe3 and Andrew Pickles1
* Corresponding author: Kimberly Goldsmith
Author Affiliations
1 Institute of Psychiatry, King's College London, DeCrespigny Park, London, SE5 8AF, UK
2 Wolfson Institute of Preventative Medicine, Queen Mary, University of London, EC1M 6BQ, UK
3 Department of Psychiatry, University of Oxford, OX3 7JX , UK
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Trials 2011, 12(Suppl 1):A144 doi:10.1186/1745-6215-12-S1-A144
The electronic version of this article is the complete one and can be found online at: http://www.trialsjournal.com/content/12/S1/A144
Published: 13 December 2011
It's free at: http://www.trialsjournal.com/content/12/S1/A144
It's late here so on a first read I'm having difficulty understanding it. Perhaps together we can break it down.