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Hi Cort,
I would welcome a source for the final paragraph inferring that NGS will be used in the XMRV study that includes Ruscetti and Mikovits please.
There are two studies that Lipkin is involved with as I understand it and I have not heard mention that NGS will be used in the XMRV-related one before.
Admittedly the details of both studies are sketchy and to be honest I don't know if NGS is a generalised term (I have yet to try and read about it specifically), but I understood that the 3 lab XMRV study would be trying once again to replicate the results of Lombardi et al.
Am happy to be corrected of course.
Also, did you happen to see the update from Cohen about the Mikovits legal dispute? He attached it to his article on 22/12/11: http://news.sciencemag.org/scienceinsider/2011/12/civil-court-rules-against-chronic.html?ref=hp
Personally, I couldn't understand what Freeman was talking about or where his confidence stems from. Then again it comes with the job I suppose - being a defense lawyer.
This is nuts. First, the judge should be aware of the international nature of this case, and the need for people to see what Mikovits had to say for herself, and why he decided against her. Next, Mikovits attorney saying it's wonderful that she lost, because it's all his fault for missing the deadlines. Is this a real trial, or something from Franz Kafka?
Dr. Mikovits criminal attorney, Scott Freeman, stated that the ruling against Dr. Mikovits was wonderful and was mostly due to her civil attorney's failing to meet deadlines.
The Judge also stated that Dr. Mikovits had flouted his instructions to return the materials.
Clarification
Freeman is doctor's criminal attorney not her civil attorney. He was referring to her civil attorney's inability to met court deadlines. I have amended it to this:
That was taken from Caroline and I suppose her conversation with Ian Lipkin. I can try and get in touch with her. It does sound like there's something extra in there that we didn't expect. I suppose it could be that they are not using their old protocols but are going with the new technology. I agree its confusing. I will try and get in touch with her.
The Next Generation Sequencing will be more used in the future, because of the major setbacks of the PCR.
Hi Cort,
Err... me again...
From your article above:
'Dr. Mikovits legal troubles continue but shes back at work on XMRV. On December 15th Nature News reported Dr. Mikovits and Dr. Ruscetti will finish the 2.3 million dollar Lipkin XMRV study funded by the NAIAD.'
Nature: March 2011: http://www.nature.com/news/2011/110314/full/471282a.html
Others, too, are rallying for a definitive answer. Ian Lipkin, a microbial epidemiologist at Columbia University in New York, has a reputation for getting to the bottom of mysterious diseasepathogen links. His team debunked the association between Borna disease virus and chronic fatigue, for example. Now he is spearheading the $1.3-million effort funded by the US government.
He is leaving the testing to three labs: Mikovits's at the WPI, Alter's at the NIH and the CDC. Each will receive coded samples of white blood cells and plasma from 150 patients with chronic fatigue and from 150 healthy controls. The labs will test for XMRV using their method of choice. Lipkin will crunch the data and unblind the samples.
But even if a study confirms the link to chronic fatigue, it won't be able to determine whether the virus is the cause. XMRV could, for example, be an opportunistic infection affecting those whose immune systems are already dampened by chronic fatigue. Even Mikovits can only hypothesize as to how it might cause disease.'
I have written to NIAIDS asking for details as I couldn't find anything on their website. Will post if they reply with anything conclusive.
Fire
That was a very bad move by Mikovits. Obviously we dont know her reasons, or what advise she was given, but you just dont get away with ignoring the judges instructions. I cant help but think that this must have had a bearing on the eventual outcome, as Judges just dont allow you to get away with that sort of behaviour.
Pleased to hear that Lipkin is open to the possibility that Mitkovits' results may have a relation to some other virus. At least she has the chance to prove there is something if she really still believes that. It certainly looks like she needs to find it to lessen the presure on her.
The winning of the civil case means that Dr. Mikovits is liable for the attorney fees the WPI has incurred thus far and opens the way for criminal charges of theft and possession of stolen property and cash awards against Dr. Mikovits. Dr. Mikovits attorney, Scott Freeman, continued his own set of striking comments by stating that the ruling against Dr. Mikovits was wonderful and was mostly due to his failing to meet deadlines. stated Dr. Mikovits was innocent because the materials taken belonged to her.
The next arraignment for Dr. Mikovits is January 10th, 2012.