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I wouldn't think they would go that far to definitively say that. That's quite a statement from a huge Institute!The association of XMRV with cancers and diseases in humans has now been proven to be due to contamination from laboratory experiments. (Question 5)
Ooof, that's quite heavy. But Ruscetti is from the NCI too. And he will chair the XMRV symposium on the 9th. So what does this mean? As long as we don't hear from him, we can of course not know for sure. But it's important what he thinks. As long as he doesn't share this view it's certainly not a fact for me. What we can probably say now is that the "official" NCI line is what we can see on this page. So it looks at least as if this group has more influence in the NCI than Ruscetti's.
In addition, a sample of the XMRV viruses reported in the 2009 article has been cultivated from patient samples and was analyzed at NCI. In contrast to the original findings, the new data suggest it is unlikely that these XMRVs were derived from infected patients. Instead, like the other XMRVs that have been sequenced, they appear to be laboratory contaminants.
Using highly-sensitive XMRV DNA detection techniques (similar to those that have become the gold standard for HIV), coupled with methods to detect mouse DNA, NCI researchers tested new, independently-collected serum samples from a small selection of patients reported to be infected in the original 2009 Science publication that hypothesized a connection between XMRV and CFS. This analysis indicated significant levels of mouse DNA contamination in several of these samples; however, there was no evidence that any of the people tested a second time had been infected with XMRV.
so singh's work is also in jeopardy then? wow
ruscetti seemed so sure. i hope he hasnt jumped ship, too. he's the kind of guy you don't mess with lol
I think this study explains why...they got ahold of some original samples and sequenced them and concluded that they all looked like the 22RV1 lab strain.
So XMRV is there in the samples...but it looks like it came from a lab not from humans. They also found evidence of contamination in some of the patients they retested and when they looked again they didn't find any XMRV...Think about this...they were able to find XMRV the first time...so they can find it...but when they retested those patients taking samples that did not come from the WPI - they were unable to find it....That's strong stuff...