I am going to do a few blogposts on this subject and am working on one relating to 'modelling' the relationship between the gut microbiome and ME/CFS.
I have studied and worked in the field of species differences for several years.
I have recently observed significant parallels between the twin fallacies of the pseudoscience of the psychological model of ME/CFS and the pseudoscience of animal 'models'.
Both of these fallacies have permeated and saturated the scientific and public discourse so that most people don't think to question their validity.
But here are some quotes from people who have, many of them scientists:
from leaflet produced by Doctors and Lawyers for Responsible Medicine
Dr Madeleine Petrovic, Doctor in Law, Austria
Michael Mansfield, QC, Britain
Professor Pietro Croce, MD, pathologist, Italy. Member, College of American Pathologists.
Dr Max Mader, GP, Graz, Austria, 1908
Dr G.F. Walker, Medical World, Dec.8, 1933
Sir George Pickering, Regius Professor of Medicine at the University of Oxford, British Medical Journal, Dec. 26, 1964
Dr Peter Mansfield, GP, Founder President of ‘Doctors in Britain against Animal Experiments’. Animal Experimentation in Medicine: the Case Against, May 1990
Dr Andre Menache, MRCVS, Israel
from Dr Hadwen Trust Annual Review 2000
Dr Jane Goodall, primatologist
from Dr Hadwen Trust Millennium Review
Dr Walter Hadwen, physician, 1923
from booklet produced by the Humane Society of the United States “Experts’ Statements on Dissection"
David O. Wiebers, MD, neurologist
Eric Dunayer, VMD, veterinarian
Gloria J. Binkowski, VMD, veterinarian
from information sheet produced by Europeans for Medical Advancement (EFMA)
Dr Ray Greek, MD
from The Guardian (UK), Wednesday July 5 2000
Dr Ray Greek, Susan Green, EFMA
from 1997 Animal Aid report Human Tissue: the neglected resource
Professor Fox, University of Manchester Medical School
Paul Townsend, Plastic Surgeon, Frenchay Hospital, Bristol
from Liberating Science, Animal Aid’s manifesto for humane research
Dr Robert Sharpe, former scientific advisor to Animal Aid
Harold Hewitt, former animal researcher.
Dr Robert Sharpe
from 'Genetic Prediction: What are the Limits?', Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences, vol. 32, Issue 4, December 2001 pp. 619-33
Andrew O.M. Wilkie, Weatherall Institute of Molecular Medicine, Oxford University
from the Seattle Post Intelligencer http://www.seattlepi.com
Letters to the Editor, Thursday August 8th 2002
Neal Barnard, M.D.
President, Physicians Committee for Responsible Medicine
from British Medical Journal
7 August 2002
Dr Pandora Pound, Research Fellow, University of Bristol, Department of Social Medicine, Canynge Hall, Whiteladies Road, Bristol BS82PR
Professor Shah Ebrahim
from Cambridge News, 25 September 2002
Dr Pandora Pound
from website of Europeans for Medical Advancement (EFMA): www.curedisease.net
Professor Michael Balls (European Centre for the Validation of Alternative Methods ECVAM), Leading Edge, BBC Radio 4 March 2000.
from 'Animal Experimentation - the medico-legal alibi', a paper on website of Doctors and Lawyers for responsible Medicine: www.dlrm.org
Dr Ralph Heywood, past scientific director of Huntington Research Centre (U.K.), speaking at a 1989 scientific workshop held at the Ciba Foundation
W.C.Roberts, American Journal of Cardiology, vol. 66 p.896
(re research on strokes)Researchers at the Mayo clinic, in D.O.Wiebers et al., Stroke, vol. 21 pp1-3
Thomas E. Wagner, senior scientist at Ohio University’s Edison Biotechnology Institute, in The Columbus Despatch, 20th March 1998, in Sacred Cows and Golden Geese
Dr Albert Sabin, developer of the polio vaccine, as quoted in Vivisection Unveiled (1997), Jon Carpenter Publishing, p.47
D.J.Galloway, Cancer Surveys, vol. 8 pp. 169-88
C.Dollery in Risk-benefit in Drug Research, ed. Cavalla, 1981 p.87
The Lancet, 25th June 1977 pp. 1348-9
Dr Irwin Bross, former director of the Sloan-Kettering cancer research institute (the largest in the world), Testimony before US Congress, 1981, cited in Sacred Cows and Golden Geese
Atlanta Journal Constitution, 21st September 1997
Dr Ray Greek, President of Americans for Medical Advancement, in ‘Monkeying with their lives, and ours...’, NAVS USA newsletter 2001, www.navs.org
...many experts agree thatJournal of the American Medical Association, vol. 277 pp. 813-17
(Cambridge University) researchers claim their intention was to advance treatment of Huntington’s Disease, even while admitting that the brain damage they inflicted (on marmosets)A.L. Kendall et al., Brain, vol. 123, part 7 pp. 1442-58
Other research shows a link between garden pesticide usage and Parkinson’s disease.
New Scientist, vol. 168: 2264 p. 16
Fisher, R.S. Brain Research Reviews vol. 14 pp. 245-78
T. Jacks, Science, 7th November 1997, vol. 278 p. 1041
Dr Richard Klausner, director of America's National Cancer Institute, Los Angeles Times, 6th May 1998
Philip Abelson, editor, Science, 1992, vol. 255 p. 141
Dr Moneim Fadali, MD, FACS, Cardiovascular and Thoracic Surgeon, USA, Animal Experimentation, A Harvest of Shame, Hidden Springs Press, 1996
Dr Irwin Bross, Fundamental and Applied Toxicology, November 1982
Journal of the American Medical Association, 1998, vol. 279, pp. 1200-1205 & 1216-17
New Scientist, 19th September 1998
According to Dr Ray Greek, our unscrupulous dependence on animal data means these deathsSacred Cows and Golden Geese
E.J.H. Moore, The Lancet, 26th April, 1986 p. 975
German surgeon Werner Hartinger, 1989, Sacred Cows and Golden Geese p. 77
British pharmaceutical company Pharmagene, New Scientist, 31st August 1996, vol. 151 p. 4
I. Asimov, Asimov's Biographical Encyclopaedia of Science and Technology, second edition, Doubleday and company, 1982
R. Greek, Specious Science, Continuum Publishers, 2002
Claude Reiss, Alzheim' R&D, Paris
from Why Animal Experiments Must Stop by Dr Vernon Coleman
Vernon Coleman, former GP, 1991
from 'Winning the Medical and Scientific Arguments' (2000) by Dr Vernon Coleman
from the Journal of American College of Surgeons, vol. 195 Issue 5 (November 2002) Pages 627-629
Dr James D Gallagher, Director of Medical Research at Lederle Laboratories, in Journal of the American Medical Association, 1964
from 'Alternatives to Animal Research'
Michael Balls, Ph.D., former Director, ECVAM, 2002
Michael Balls, Ph.D., former Director, ECVAM, 1998
William Russell, Ph.D., founder of modern alternatives movement, 2003
Nobel Prize winner Sir Peter Medawar
John McArdle, PhD
(all of which are 'tested' on animals) (BMJ, 1988, vol. 296, pp.761-764)
Dr Murry Cohen, past chairman of the MRMC (Medical Research Modernisation Committee) in the U.S., speaking at the International Conference "Future Medical Research Without the Use of Animals: Facing the Challenge" in Tel-Aviv, May 1990
Ganellin, C.R. (1994) 'Past approaches to discovering new drugs as medicines,' in Medicinal Chemistry - Principles and Practice, King, F.D. (ed.), Royal Society of Chemistry, ch. 13, pp. 189-205
R. Kumar, GlaxoSmithKline R & D, USA, Breast Cancer Research 2003, % (Suppl. 1): 15
Kathleen Murray, director of transgenic services at Charles Rivers, New Scientist, Feb. 4, 2002
from The Orlando Sentinel, June 25, 1990
“Animal Testing: Why a Doctor Opposes It"
Stoller, Kenneth, M.D.
Orest Hurko, MD, and J. Lynn Rutkowski, PhD, Translational Medicine Breaks Bottlenecks, Drug Discovery & Development
Michael O. Leavitt, secretary of the Department of Health and Human Services, at the FDA news conference.
Journal of the American Medical Association, vol. 295, No 9, pp. 988-9
Re claim by Association of Medical Research Charities thatAdvertising Standards Authority adjudication 5th October 2005
Sacred Cows and Golden Geese
Authors: C. Ray Greek, MD and Jean Swingle Greek, DVM
Publisher: The Continuum International Publishing Group Inc
1st Published 2000
from The Lancet, Vol 377, Issue 9781, page 1915, June 4, 2011:
We urge you to act now to ensure that the best technologies currently available are used to establish the safety of medicines for patients.
Kathy Archibald, Robert Coleman, Christopher Foster, on behalf of 19 other signatories who are:
1. Dr Kelly BéruBé (PhD), Director, Lung & Particle Research Group, Cardiff
2. Dr David Bunton (PhD), Chief Executive Officer, Biopta, Ltd, Glasgow
3. Dr Margaret Clotworthy (PhD), Director, Human Focused Testing, Cambridge
4. Dr Ann Cooreman (PhD), Chief Operating Officer, Tissue Solutions Ltd, Clydebank
5. Professor Anne Dickinson, Director, Alcyomics Ltd, Newcastle upon Tyne
6. Professor Barry Fuller, Department of Surgery, UCL Medical School, London
7. Dr B J Nathan Griffiths (PhD), Commercial Director, Abcellute & Abcellute Tissue Bank, Cardiff
8. Dr Morag McFarlane (PhD), Chief Scientific Officer, Tissue Solutions Ltd,
9. Professor Chris Hillier (PhD), Professor of Physiology, Glasgow Caledonian University
10. Anup Patel, Consultant Urological Surgeon, St. Mary’s Hospital, Imperial College Healthcare NHS Trust and Chairman of Clinical Studies Committee, European Association of Urology Research Foundation
11. Professor Barbara Pierscionek, Head of Vision Science Research, University of Ulster
12. Dr Cathy Prescott (PhD), Director, Biolatris Ltd, Cambridge and Chair of the UK National Stem Cell Network Advisory Committee
13. James Root, Senior Scientist, Pfizer, Sandwich
14. Professor Gerry Thomas, Chair in Molecular Pathology, Imperial College, London and Director of Scientific Services, Wales Cancer Bank
15. Dr Katya Tsaioun (PhD), Chief Scientific Officer, Cyprotex, Macclesfield
16. Dr J Malcolm Wilkinson (PhD), Chief Executive Officer, Kirkstall Ltd, Sheffield
17. Professor Sir Ian Wilmut FRS FRSE, MRC Centre for Regenerative Medicine, University of Edinburgh
18. Dr Amanda Woodrooffe (PhD), General Manager, Asterand UK Ltd, Royston
19. Dr Karen L Wright (PhD), Peel Trust Lecturer in Biomedicine, Lancaster University
Scientist Tony Baxter, who runs a research lab in Cheshire said June 2011:
The flawed paradigm of animal 'models'
Blog entry posted by MeSci, Feb 11, 2014.