Blog entries from anciendaze

anciendaze has a total of 85 entries.

  1. anciendaze
    At the moment my present idea of exercise is more appropriate for playing with the family dog: "Sit up. Roll over. Play dead." My Memorial Day weekend was the kind of memorable occasion I'd like to forget. I had a minor illness which others here will recognize as a serious problem when it comes on top of ME/CFS. It was nothing more than an apparent viral upper respiratory infection with...
    anciendaze, Jun 1, 2016
  2. anciendaze
    It seems those of us who are so perverse we refuse to fit in convenient medical diagnostic categories with neat billing codes can't help but stumble around in minefields of medical controversy. This is one of them. The name in this title is a sort of nickname for a molecule with full name α-N-acetylgalactosaminidase. (Such shorthand is as essential to avoid nominal overload as identifying...
    anciendaze, Mar 22, 2016
  3. anciendaze
    Here is another more personal post. It started out as a message for friends alarmed by reports they saw in the general press. This has become a topic in the general press because it appeared in "The Lancet" with apparently authoritative backing. You will have no trouble finding alarming headlines about Chronic Fatigue Syndrome (CFS) and suicide. You can also find serious errors of...
    anciendaze, Feb 26, 2016
  4. anciendaze
    The following is from a letter written to explain this illness to someone well-intentioned but misinformed. I've tried to avoid the heavy use of bibliographic references and other academic practices to concentrate on a limited number of objective measures intelligible to almost anyone. It turns out that PACE was a good source for such data, if you avoid their interpretations. This is a...
    anciendaze, Jan 31, 2016
  5. anciendaze
    We now have explicit evidence that a common retrovirus in cattle is transmitted to humans, and associated with lethal disease. This falls short of academic standards for determining etiology, but that may not be very important when it points to a major risk factor. There are many risk factors doctors take very seriously which have yet to be conclusively tied to causation. If you doubt a...
    anciendaze, Sep 21, 2015
  6. anciendaze
    The Human Genome Project found essentially all of the "coding DNA" being transcribed into proteins back in 2003. The first draft of a human genome was declared complete, though there were certainly loose ends to be tied up. One surprise at the time was that the protein coding genes identified were far less numerous than expected. Humans have 22,000, but mice have 23,000, even fruit flies...
    anciendaze, Aug 10, 2015
  7. anciendaze
    If knowledge itself is power, what results from profound ignorance? Whatever that is, I think it describes the way medicine has dealt with the immune system. Prior to Pasteur (ca. 1870) I would describe understanding of immunology as entirely anecdotal. We have learned a lot since then, but haven't come quite as far as you might think. It would now be awkward to produce baseball cards for...
    anciendaze, Jun 10, 2015
  8. anciendaze
    This is a term in graphic arts for a trick that fools the eye, a deliberate optical illusion. Famous examples include recesses with statues, or windows with distant vistas, which turn out to be flat images on a wall, or huge, complicated domes or high vaults which turn out to be painted on flat ceilings or low vaults. The practice is often said to have begun with Renaissance discoveries of...
    anciendaze, Jun 3, 2015
  9. anciendaze
    What does it mean to improve public health? There are many measures based on what goes into the process, but fewer based on what results. Since zero input will produce zero output we tend to assume positive results must be proportional to effort expended. When large numbers of intelligent, educated, hard-working people depend on this for income you can be sure such a reporting bias will...
    anciendaze, Mar 14, 2015
  10. anciendaze
    If a tree falls in the woods, and a statistician declares this a random event, does it make a sound? This question ran through my mind when I read responses to news out of Columbia University concerning ME/CFS/SEID/WTF. The report on plasma immune signatures of physiological pathology in the first three years after onset of ME/CFS in the Hornig/Lipkin study is welcome news because it is...
    anciendaze, Mar 9, 2015
  11. anciendaze
    Note: this is actually a follow-up on my previous post The Sound of Silence. This was provoked by "expert opinions" on the Hornig/Lipkin study made public by the UK's Science Media Center, and in particular the comment that this was only "a small study". Readers looking for more topical material will be disappointed. When I commented on the omissions in the PACE trial one might have thought...
    anciendaze, Mar 2, 2015
  12. anciendaze
    There have long been problems in reconstructing the history of China, because several dynasties went to some lengths to erase the history of preceding dynasties. The classic case is the Qin (Chin) dynasty founded by Qin Shi Huang. You can tell this was remarkably successful because the resulting country is still called China. This took place in 221 B.C.E., by our calendars. This even...
    anciendaze, Feb 15, 2015
  13. anciendaze
    I'll start with some lighter material which would get this deleted as off topic if this were not a blog. A little gentle humor is not misplaced when emotions run high. We'll see how it relates as we go on. There have recently been reports of a major security breach at Anthem involving data on millions of patients. The consequences are still developing. While this did not include actual...
    anciendaze, Feb 14, 2015
  14. anciendaze
    A great deal of noise has been made over various things the authors of the PACE study have claimed in publications or spoken statements. What has received much less attention is the remarkable extent to which they have remained silent on very significant aspects of that trial. The continuing stream of papers based on the flawed primary study prompts me to explore this neglected aspect. Did...
    anciendaze, Feb 1, 2015
  15. anciendaze
    The series of publications stemming from the PACE trial continues to roll on with the inevitability of a juggernaut or tumbrel. The venue for this series of reactionary proclamations has been The Lancet and specialty journals of that group. People might ask how such a prestigious publication could not just allow such expressions of prejudice and poorly-supported claims to not just make it...
    anciendaze, Feb 1, 2015